The indications for the prescription of statins have broadened over the years. Initial studies supported the use of statins in secondary prevention for cardiovascular disease, or as primary prevention only when the risk of cardiovascular disease was significantly raised. Currently, based on clinical trials, statins also play an important role in myocardial infarction, stroke and peripheral arterial disease. There are still some questions regarding the use of statins in hypertension, heart failure and atrial fibrillation.
Statins improve the postoperative condition and prognosis and decrease the risk of postoperative complications in patients subjected to surgical coronary revascularization. However, there are still a few aspects that need to be explained, especially the role of statins in patients undergoing surgical revascularization and concomitant valve surgery, or valve surgery alone. There is still little knowledge regarding application of statins in patients with heart failure subjected to surgical revascularization.