A Systematic Review of Case Reports on the Co-occurrence of Cutaneous Lupus Erythematosus and Psoriasis

Izabela Staniszewska; Lidia Mądrzak; Hanna Piekarczyk; Milena Baran; Agnieszka Kalińska-Bienias

doi:10.5114/dr.2025.152182

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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1/2025
vol. 112

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abstract:

Review article

A Systematic Review of Case Reports on the Co-occurrence of Cutaneous Lupus Erythematosus and Psoriasis

Izabela Staniszewska

¹

,

Lidia Mądrzak

¹

,

Hanna Piekarczyk

¹

,

Milena Baran

¹

,

Agnieszka Kalińska-Bienias

¹

Department of Dermatology, Medical University of Warsaw, Warsaw, Poland

Dermatol Rev/Przegl Dermatol 2025, 112, 19-26

DOI: https://doi.org/10.5114/dr.2025.152182

Online publish date: 2025/05/15

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Introduction:
Cutaneous lupus erythematosus is a connective tissue disease that may occur independently or with systemic lupus erythematosus. Psoriasis is a chronic skin disease often linked to metabolic syndrome. No systematic review has explored the coexistence of cutaneous lupus erythematosus and psoriasis.

Methods:
Following PRISMA guidelines, databases (PubMed, EMBASE, Scopus, Web of Science) were searched for articles published up to December 2023.

Results:
17 articles involving 17 patients with cutaneous lupus erythematosus and psoriasis were analysed. Subacute cutaneous lupus erythematosus was the most common subtype (58.8%), and plaque psoriasis predominated (82.35%). Positive ANA antibodies were found in 82.35% of patients, with UV hypersensitivity in 23.5%. Cutaneous lupus erythematosus lesions were mainly located on the head-neck-face (62.5%); psoriasis appeared mostly on the legs (62.5%). The most common treatment was discontinuing biologics for psoriasis (37.6%).

Conclusions:
The co-occurrence of cutaneous lupus erythematosus and psoriasis is rare, with subacute cutaneous lupus erythematosus and plaque psoriasis being the most common combination.

keywords:

psoriasis, connective tissue, cutaneous lupus erythematosus

Indeks osobowy

A Systematic Review of Case Reports on the Co-occurrence of Cutaneous Lupus Erythematosus and Psoriasis

Izabela Staniszewska 1 , Lidia Mądrzak 1 , Hanna Piekarczyk 1 , Milena Baran 1 , Agnieszka Kalińska-Bienias 1

psoriasis, connective tissue, cutaneous lupus erythematosus

Izabela Staniszewska

¹

,

Lidia Mądrzak

¹

,

Hanna Piekarczyk

¹

,

Milena Baran

¹

,

Agnieszka Kalińska-Bienias

¹