eISSN: 1897-4309
ISSN: 1428-2526
Contemporary Oncology/Współczesna Onkologia
Current issue Archive Manuscripts accepted About the journal Supplements Addendum Special Issues Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
5/2012
vol. 16
 
Share:
Share:
abstract:
Review paper

Acute pulmonary embolus in the course of cancer

Marta Biedka
,
Ewa Ziółkowska
,
Wiesława Windorbska

Wspolczesna Onkol 2012; 16 (5): 388–393
Online publish date: 2012/11/20
View full text Get citation
 
PlumX metrics:
Risk of pulmonary embolism (PE) is relatively high in patients with advanced chronic diseases, particularly with malignancies. Most patients with cancer have blood coagulation test abnormalities indicative of up-regulation of the coagulation cascade, increased platelet activation and aggregation. Pulmonary thromboembolism is common in patients with any cancer and incidence is increased by surgery, chemotherapy, radiotherapy and disease progression. Manifestations range from small asymptomatic to life-threatening central PE with subsequent hypotension and cardiogenic shock. Diagnostic algorithms utilizing various noninvasive tests have been developed to determine the pretest probability of PE results of D-dimer assay, chest radiography ECG and computed tomography. The mortality in untreated PE is high (30%) but appropriate treatment may decrease it to 2–18%. The current recommended treatment for massive pulmonary embolus is either thrombolytic therapy or surgical embolectomy.
keywords:

embolus, cancer, thrombosis

Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.