Antiviral therapy of chronic HBV infection in pregnancy

Julita Nikolajuk-Stasiuk; Agnieszka Czauz-Andrzejuk; Tadeusz Łapiński

doi:10.5114/ceh.2015.58041

eISSN: 2449-8238
ISSN: 2392-1099

Clinical and Experimental Hepatology

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abstract:

Case report

Antiviral therapy of chronic HBV infection in pregnancy

Julita Nikolajuk-Stasiuk

,

Agnieszka Czauz-Andrzejuk

,

Tadeusz Wojciech Łapiński

Clinical and Experimental HEPATOLOGY 2015; 4: 131–132

DOI: https://doi.org/10.5114/ceh.2015.58041

Online publish date: 2016/02/25

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We describe a 27-year-old hepatitis B virus (HBV)-infected pregnant woman, with a history of miscarriage a year ago. The patient has been HBsAg and HBeAg positive for 20 years but has never been treated for HBV infection, because of stable elevated alanine aminotransferase (ALT) activity and high viral load. Treatment with tenofovir disoproxil was introduced in the 10th week of pregnancy and HBV DNA became undetectable. The clinical course of pregnancy was normal and the patient gave birth by caesarean section to a healthy child. At birth the newborn was HBsAg negative, after 3 months of follow-up is healthy, and evaluation of HBV status will be scheduled shortly. The decision to treat HBV infection during pregnancy should be individualized.

keywords:

Antiviral therapy of chronic HBV infection in pregnancy

Julita Nikolajuk-Stasiuk , Agnieszka Czauz-Andrzejuk , Tadeusz Wojciech Łapiński

pregnancy, HBV infection, treatment

Julita Nikolajuk-Stasiuk

,

Agnieszka Czauz-Andrzejuk

,

Tadeusz Wojciech Łapiński