Beta-blockers in particular clinical disorders – does the shoe fit Cinderella?

Piotr Kukla; Danuta Czarnecka

ISSN: 1505-8409

Przewodnik Lekarza/Guide for GPs

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4/2008
vol. 11

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abstract:

Beta-blockers in particular clinical disorders – does the shoe fit Cinderella?

Piotr Kukla

,

Danuta Czarnecka

Przew Lek 2008; 4:40-47

Online publish date: 2008/09/26

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bBeta-blockers are competitive agonists of catecholamines acting on the beta adrenergic receptor. What are the limitations in using beta-blockers? The most important limitations are: acute heart failure, conduction disturbances, pulmonary side effects and metabolic disorders. Today, having a wide spectrum of beta-blockers, we can choose for each patient with accompanying diseases the best individual one. To treat heart failure the following beta-blockers are recommended: carvedilol, long-lasting metoprolol, bisoprolol and nebivolol in older patients. In the case of accompanying renal failure the preferred one should be metoprolol and carvedilol. Carvedilol should be avoided in renal failure with accompanying anaemia because it could intensify the anaemia. In metabolic syndrome the preferred beta-blocker is carvedilol. In patients with pulmonary diseases the most recommended are celiprolol and nebivolol.

keywords:

Beta-blockers in particular clinical disorders – does the shoe fit Cinderella?

Piotr Kukla , Danuta Czarnecka

beta-blockers, heart failure, pulmonary diseases, renal failure, metabolic syndrome

Piotr Kukla

,

Danuta Czarnecka