Malignant eccrine spiradenoma is an extremely rare sweat-gland tumour. Herein we aimed to present an 81-year-old woman with malignant eccrine spiradenoma repeated on the thigh and metachronous lung cancer. She presented with a palpable swelling in the right thigh region. Her systemic screening was normal and excisional biopsy was performed. A diagnosis of malignant eccrine spiradenoma was made. Thirty-two months later, the tumour recurred in the same region. The tumour was excised again. Lymph node metastasis was also detected in lymph node dissection. Fifteen months later, the tumour recurred again in the same place. In addition, lymph node metastasis and bone metastasis were found. Palliative radiotherapy was performed for the involvement of the right femur. The treatment for metachronous lung cancer could not be given because of the patient’s age and performance, and she could not be given additional treatment for the same reasons.