Intracystic papillary carcinoma (IPC) is one of the rare malignant tumours of the breast. It occurs communally in postmenopausal women with average age between 55 and 67 years old. It can be clinically asymptomatic, or it presents with a breast mass or areolar changes. Using imaging techniques, IPC is usually characterised by benign features. IPC should be considered in the evaluation and differential diagnosis of cystic lesions observed in postmenopausal women, and it has a more positive prognosis than that of ductal carcinoma in situ (DCIS). Although segmental mastectomy is recommended for the treatment of such lesions, no universal consensus exists on adjuvant therapies.

In this case study, the authors present two female patients, aged 68 and 43 years, diagnosed with IPC, with reference to the literature.