Dermatology Review
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eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
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6/2025
vol. 112
 
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Case report

Cerebrospinal Meningitis in the Course of Secondary Syphilis

Maja Kleniewska
1
,
Hubert Kleniewski
2
,
Agnieszka B. Owczarczyk-Saczonek
1

  1. Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, University of Warmia and Mazury, Olsztyn, Poland
  2. Department of Radiology, Children’s Hospital, Olsztyn, Poland
Dermatol Rev/Przegl Dermatol 2025, 112, 378-381
Online publish date: 2026/02/28
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1. Tudor M.E., Al Aboud A.M., Leslie S.W., Gossman W.: Syphilis. 2024 Aug 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–.
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10. Hamill M.M., Ghanem K.G., Tuddenham S.: State-of-the-art review: neurosyphilis. Clin Infect Dis 2024, 78, e57-e68.
11. Wojas-Pelc A., Pastuszczak M., Serwin A., Rudnicka I., Majewski S., Czajkowski R., et al.: Syphilis. Diagnostic and therapeutic recommendations of the Polish Dermatological Society. Part 2: neurosyphilis, syphilis in pregnancy and congenital syphilis. Dermatol Rev 2018, 105, 582-592.
12. Matsumoto H., Suzuki S., Nagata M., Senoo T., Watanabe M., Kawashima H.: Clinical features of syphilis patients with ocular symptoms as the initial manifestation. Clin Ophthalmol 2023, 17, 2901-2907.
13. Workowski K.A., Bachmann L.H.: Centers for disease control and prevention’s sexually transmitted diseases infection guidelines. Clin Infect Dis 2022, 74 (Suppl 2), S89-S94.
14. Tuddenham S., Katz S.S., Ghanem K.G.: Syphilis laboratory guidelines: performance characteristics of nontreponemal antibody tests. Clin Infect Dis 2020, 71 (Suppl 1), S21-S42.
15. Ito H.: Enhancing neurosyphilis diagnosis: evaluating serum biomarkers as non-invasive alternatives to lumbar puncture. Clin Infect Dis 2024, 78, 1384-1385.
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17. Woźniacka A., Sysa-Jędrzejowska A., Jurowski P., Jabłkowski M., Kot M.: Morbus Behçet – a rare disease in Central Europe. Arch Med Sci 2015, 11, 1189-1196.
18. Whiting C., Schwartzman G., Khachemoune A.: Syphilis in dermatology: recognition and management. Am J Clin Dermatol 2023, 24, 287-297.
19. Wojas-Pelc A., Pastuszczak M., Serwin A., Rudnicka I., Majewski S., Czajkowski R., et al.: Syphilis. Diagnostic and therapeutic recommendations of the Polish Dermatological Society. Part 1: early and late syphilis. Dermatol Rev 2018, 105, 563-581.
Copyright: © 2026 Polish Dermatological Association. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.



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