Advances in Interventional Cardiology
eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
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SCImago Journal & Country Rank
1/2026
vol. 22
 
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abstract:
Original paper

Circumstances and clinical significance of cardiac troponin T elevation following transvenous lead extraction

Jarosław Kosior
1
,
Dorota Nowosielecka
2, 3
,
Wojciech Jacheć
4
,
Anna Polewczyk
5, 6
,
Andrzej W. Kutarski
4

  1. Department of Cardiology, Masovian Specialistic Hospital, Radom, Poland
  2. Department of Cardiac Surgery, The Pope John Paul II Province Hospital, Zamość, Poland
  3. Faculty of Health Sciences, Academy of Zamość, Poland
  4. 2nd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Silesian Medical University in Katowice, Poland
  5. Department of Physiology, Pathophysiology and Clinical Immunology, Collegium Medicum, Jan Kochanowski University, Kielce, Poland
  6. Department of Cardiac Surgery, Swietokrzyskie Cardiology Center, Kielce, Poland
Adv Interv Cardiol 2026; 22, 1 (83): 103–113
Online publish date: 2026/03/10
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Introduction
Little is known about cardiac troponin T (cTnT) release during transvenous lead extraction (TLE).

Aim
The aim of the study was to identify factors influencing the intensity of cTnT release during TLE and to investigate whether the increase in cTnT levels after TLE has any prognostic significance for medium-term survival.

Material and methods
Retrospective analysis of a TLE database.

Results
In 166 consecutive patients who underwent the TLE procedure, an elevated hs cTnT level > 0.014 µg/l was present in almost 100%. The increase in troponin level 8 h after TLE (DcTnT8) was 900% of average and 400% of the median initial concentration. The factors most strongly associated with cTnT release during TLE were the age of the oldest extracted leads and the number of points on the Complex Indicator of Difficulty (CID) score. Additional procedural factors included the occurrence of technical problems, the need for second-line tools, hypotension > 1 min appearance, and traction on cardiac structures visible on transoesophageal echocardiography.

Conclusions
Elevated cTnT levels are observed following nearly all TLE procedures; however, they do not impact the incidence of major complications, perioperative mortality, or long-term survival rates. Longer dwelling time of the extracted leads and the procedural complexity of TLE are the primary determinants of the magnitude of cardiac troponin release.

keywords:

troponin T release, lead extraction, non-ischemic troponin release


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