eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
5/2020
vol. 37
 
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abstract:
Original paper

Clinical picture and treatment of cutaneous lesions in patients with neurofibromatosis type 1

Marta Fijałkowska
1
,
Bogusław Antoszewski
1

1.
Department of Plastic, Reconstructive and Aesthetic Surgery, Second Chair of Surgery, Medical University of Lodz, Lodz, Poland
Adv Dermatol Allergol 2020; XXXVII (5): 781-784
Online publish date: 2020/11/07
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Introduction
The most common type of neurofibromatosis is Recklinghausen disease (NF-1). A major feature of NF1 is the development of localized cutaneous neurofibromas. Such types of lesions are manifested in > 99% of adults with NF1 and are responsible for major negative effects on quality of life.

Aim
To present the clinical picture of patients with NF-1 and to report authors’ own observations related to their surgical treatment.

Material and methods
A retrospective study aiming to present a group of patients with Recklinghausen disease was planned. The study was carried out in 39 patients with NF-1.

Results
All patients had cutaneous neurofibromas localized in different parts of the body. The three most frequent localizations were the abdomen, back, and face. Surgical treatment was performed in 31 patients. All patients had discomfort due to the presence of cutaneous nodules especially because their visibility and multiplicity.

Conclusions
Due to the polymorphism of the clinical picture and unpredictable course of the disease, there is no one standard of treatment of patients with Recklinghausen disease. Excision of tumours in the early stage of their development gives better functional and aesthetic results.

keywords:

neurofibromatosis type 1, neurofibroma, surgery

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