Dietary derived compounds in cancer chemoprevention

Ewa Langner; Wojciech Rzeski

doi:10.5114/wo.2012.31767

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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5/2012
vol. 16

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abstract:

Review paper

Dietary derived compounds in cancer chemoprevention

Ewa Langner

,

Wojciech Rzeski

Wspolczesna Onkol 2012; 16 (5): 394–400

DOI: https://doi.org/10.5114/wo.2012.31767

Online publish date: 2012/11/19

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Cancer chemoprevention is defined as the application of natural or synthetic agents to suppress or reverse cancer development and progression. In this field especially diet derived compounds have recently attracted researchers’ attention as potential therapeutics generally exerting low toxicity compared with regular drugs. This review presents a survey of recent findings concerning the most promising dietary chemopreventive agents such as green tea polyphenols (i.e. catechins), long-chain polyunsaturated fatty acids, carotenoids, glucosinolates/isothiocyanates, vitamins (i.e. vitamin D and folate) and minerals (i.e. calcium and selenium). Molecular targets involved in intrinsic pathways affected by these natural compounds are also shortly discussed.

keywords:

Dietary derived compounds in cancer chemoprevention

Ewa Langner , Wojciech Rzeski

cancer chemoprevention, green tea polyphenols, polyunsaturated fatty acids, glucosinolates, carotenoids

Ewa Langner

,

Wojciech Rzeski