Advances in Interventional Cardiology
eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
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1/2026
vol. 22
 
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Divergence in postoperative platelet aggregation during antiplatelet monotherapy with aspirin in the early postoperative period following coronary artery bypass grafting: initial findings

Anna Kędziora
1
,
Magdalena Kopytek
2, 3
,
Justyna Totoń-Żurańska
4
,
Piotr Śliwiński
5
,
Agnieszka Branicka
6
,
Radosław Litwinowicz
7
,
Jacek Piątek
5, 8
,
Bogusław Kapelak
5, 8

  1. Department of Cardiac Surgery and Heart Transplantation, Institute of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
  2. Krakow Center for Medical Research and Technologies, St. John Paul II Hospital, Krakow, Poland
  3. Department of Thromboembolic Disorders, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland
  4. Center for Medical Genomics OMICRON, Jagiellonian University Medical College, Krakow, Poland
  5. Department of Cardiovascular Surgery and Transplantation, St. John Paul II Hospital, Krakow, Poland
  6. Molecular Biology Laboratory, St. John Paul II Hospital, Krakow, Poland
  7. Department of Cardiac Surgery, Regional Specialist Hospital, Grudziadz, Poland
  8. Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland
Adv Interv Cardiol 2026; 22, 1 (83): 130–133
DOI: https://doi.org/10.5114/aic.2026.160052
Online publish date: 2026/03/10
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- Divergence in postoperative.pdf  [0.07 MB]
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1. Jeppsson A, Rocca B, Milojevic M, et al. 2024 EACTS Guidelines on perioperative medication in adult cardiac surgery. Eur J Cardiothorac Surg 2024; 67: ezae355.
2. Visseren FLJ, Mach F, Smulders YM, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J 2021; 42: 3227-337.
3. Vrints C, Andreotti F, Koskinas KC, et al. 2024 ESC Guidelines for the management of chronic coronary syndromes. Eur Heart J 2024; 45: 3415-537.
4. Jones WS, Mulder H, Wruck LM, et al. Comparative effectiveness of aspirin dosing in cardiovascular disease. N Engl J Med 2021; 384: 1981-90.
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7. Kulik A, Ruel M, Jneid H, et al. Secondary prevention after coronary artery bypass graft surgery: a scientific statement from the American Heart Association. Circulation 2015; 131: 927-64.
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10. Gurbel PA, Bliden KP, Tantry US. Defining platelet response to acetylsalicylic acid: the relation between inhibition of serum thromboxane B2 and agonist-induced platelet aggregation. J Thromb Thrombolysis 2021; 51: 260-4.
11. Zimmermann N, Kienzle P, Weber AA, et al. Aspirin resistance after coronary artery bypass grafting. J Thorac Cardiovasc Surg 2001; 121: 982-4.
12. Bednar F, Tencer T, Plasil P, et al. Evaluation of aspirin’s effect on platelet function early after coronary artery bypass grafting. J Cardiothorac Vasc Anesth 2012; 26: 575-80. 
13. Urbanowicz TK, Gąsecka A, Olasińska-Wiśniewska A, et al. Plasma leukocyte-derived extracellular vesicles are related to target vessel revascularization in off-pump coronary artery bypass grafting. Adv Interv Cardiol 2024; 20: 433-42.
14. Kuliczkowski W, Golanski R, Bijak M, et al. Relationship between high on aspirin platelet reactivity and oxidative stress in coronary artery by-pass grafted patients. Blood Coagul Fibrinolysis 2016; 27: 151-5.
15. Zimmermann N, Kurt M, Wenk A, et al. Is cardiopulmonary bypass a reason for aspirin resistance after coronary artery bypass grafting? Eur J Cardiothorac Surg 2005; 27: 606-10.
Copyright: © 2026 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

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