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ISSN: 1505-8409
Przewodnik Lekarza/Guide for GPs
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6/2008
vol. 11
 
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abstract:

Do we know the pathogenesis of essential hypertension?

Zbigniew Gaciong
,
Bartosz Symonides
,
Jarosław Góra
,
Grzegorz Placha

Przew Lek 2008; 6: 10-13
Online publish date: 2009/03/02
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Despite extensive research the pathogenesis of essential hypertension still remains unknown. Regulation of blood pressure includes a complex series of interacting factors which control diameter of blood vessels, their responsiveness, fluid volume and cardiac output. We made an attempt to summarize contemporary views on the role of genes and the environment, describing major mechanisms leading to hypertension.
keywords:

candidate genes, obesity, adrenergic system, vasoactive substances

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