Abstract
6/2005
vol. 22
Efficacy and safety of cis-trans-1,4-cyclohexanediol gel in the case of adult patients with rosacea, seborrheic dermatitis and facial dermatitis
PDiA 2005; XXII, 6: 271-277
Online publish date: 2005/12/28
Cis-trans-1,4-cyclohexanediol is a component of a new skin care gel for use in the treatment of skin conditions associated with inflammatory, erythematous, papulopustular and teleangiectatic skin lesions. The aim of the study was to evaluate the efficiency and safety of this product in the treatment of skin inflammation in rosacea, seborrheic dermatitis and facial dermatitis of adults. We investigated forty subjects who were evaluated in terms of clinical score (erythema, papules, pustules, teleangiectasia, and additionally itching and burning sensation) at baseline, and after 1, 2 and 3 weeks of treatment. We recorded a significant improvement of the global clinical score and a reduction of the itching and burning sensation. We did not observe any clinically relevant side effects of the treatment. Therefore, we suggest that 1,4-cyclohexanediol gel is a safe and effective cosmetic for everyday skin care, and especially for the treatment of skin conditions associated with skin inflammation in rosacea, seborrheic dermatitis and facial dermatitis.
Keywords
1,4-cyclohexanediol, skin inflammation, rosacea, soborrheic dermatitis, perioral dermatitis, face dermatitis
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