Endothelial stress ratio as a predictor of the no-reflow phenomenon in patients with acute coronary syndrome: a retrospective study
Department of Cardiology, Erzurum City Hospital, Erzurum, Türkiye
Department of Cardiology, Faculty of Medicine, Ataturk University Erzurum, Türkiye
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- Morishima I, Sone T, Okumura K, et al. Angiographic no-reflow phenomenon as a predictor of adverse long-term outcome in patients treated with percutaneous transluminal coronary angioplasty for first acute myocardial infarction. J Am Coll Cardiol 2000; 36: 1202-9.
- Niccoli G, Scalone G, Lerman A, Crea F. Coronary microvascular obstruction in acute myocardial infarction. Eur Heart J 2016; 37: 1024-33.
- Heusch G. Coronary microvascular obstruction: the new frontier in cardioprotection. Basic Res Cardiol 2019; 114: 45.
- Kloner RA. No-reflow phenomenon: maintaining vascular integrity. J Cardiovasc Pharmacol Ther 2011; 16: 244-50.
- Nicolau AM, Silva PG, Mejía HPG, et al. Molecular mechanisms of microvascular obstruction and dysfunction in percutaneous coronary interventions: from pathophysiology to therapeutics a comprehensive review. Int J Mol Sci 2025; 26: 6835.
- Zhao Y, Yang J, Ji Y, et al. Usefulness of fibrinogen-to-albumin ratio to predict no-reflow and short-term prognosis in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Heart Vessels 2019; 34: 1600-7.
- Refaat H, Tantawy A, Gamal AS, et al. Novel predictors and adverse long-term outcomes of no-reflow phenomenon in patients with acute ST elevation myocardial infarction undergoing primary PCI. Indian Heart J 2021; 73: 35-43.
- Rezkalla SH, Kloner RA. No-reflow phenomenon. Circulation 2002; 105: 656-62.
- Niccoli G, Burzotta F, Galiuto L, Crea F. Myocardial no-reflow in humans. J Am Coll Cardiol 2009; 54: 281-92.
- Ito H. No-reflow phenomenon and prognosis in acute myocardial infarction. Nat Clin Pract Cardiovasc Med 2006; 3: 499-506.
- Wang W, Ren D, Wang CS, et al. Prognostic efficacy of high-sensitivity C-reactive protein to albumin ratio in patients with acute coronary syndrome. Biomarkers Med 2019; 13: 811-20.
- Libby P, Loscalzo J, Ridker PM, et al. Inflammation, immunity, and infection in atherothrombosis: JACC review topic of the week. J Am Coll Cardiol 2018; 72: 2071-81.
-
Harrison RW, Aggarwal A, Ou FS, et al. Incidence and outcomes of
no-reflow phenomenon during percutaneous coronary intervention among
patients with acute myocardial infarction. Am
J Cardiol 2013; 111: 178-84. - Zhang L, Lin J, Luo L, et al. Analysis of risk factors for PCI no-reflow in coronary heart disease and construction of related prediction models. Am J Transl Res 2024; 16: 3733-41.
- Prasad A, Gersh BJ. Management of microvascular dysfunction and reperfusion injury. Heart 2005; 91: 1530-2.
- Ridker PM, Everett BM, Thuren T, et al. Anti-inflammatory therapy with canakinumab and prevention of cardiovascular events. N Engl J Med 2017; 377: 1119-31.
- Libby P. Inflammation in atherosclerosis. J Am Coll Cardiol 2009; 54: 2129-38.
- Marcus ML, Chilian WM, Kanatsuka H, et al. Understanding the coronary circulation through studies at the microvascular level. Circulation 1990; 82: 1-7.
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