Abstract
2/2018
vol. 105
Case report
Fetal microchimerism in a pregnant woman and risk of autoimmune disease
Dermatol Rev/Przegl Dermatol 2018, 105, 307-313
Online publish date: 2018/05/14
Autoimmune diseases most commonly affect women in their reproductive age. Many studies have attempted to link microchimeric fetal cells with the onset of autoimmune diseases after pregnancy. One of these diseases is localized scleroderma (morphea), which is a rare fibrosing disorder of the skin and underlying tissues. The etiology of morphea is unknown, but there are some predisposing factors that may induce morphea-like lesions. We present a rare case of a patient whose first cutaneous sclerotic lesions appeared in her 35th week of pregnancy. To our knowledge, to date pregnancy has not been treated as a predisposing factor for that disease, although it may be a risk factor, considering the phenomenon of fetal-maternal microchimerism.
Keywords
microchimerism, pregnancy, autoimmune disease, localized scleroderma
Coverage in
Integrated with


