Clinical and Experimental Hepatology
eISSN: 2449-8238
ISSN: 2392-1099
Clinical and Experimental Hepatology
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SCImago Journal & Country Rank
3/2025
vol. 11
 
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abstract:
Review paper

Implantation of nasobiliary drainage in treatment of severe episodes of benign recurrent intrahepatic cholestasis (BRIC) in pediatric patients

Maciej Dądalski
1
,
Tetiana Wojciechowska
1
,
Joanna Ryżko
1
,
Magda Naorniakowska
1
,
Joanna Cielecka-Kuszyk
2
,
Elżbieta Ciara
3
,
Małgorzata Sawilska-Tańska
4
,
Joanna Pawłowska
1

  1. Department of Gastroenterology, Hepatology, Nutritional Disorders, and Pediatrics, The Children’s Memorial Health Institute, Warsaw, Poland
  2. Department of Pathomorphology, Children’s Memorial Health Institute, Warsaw, Poland
  3. Department of Medical Genetics, Children’s Memorial Health Institute, Warsaw, Poland
  4. Department of Pediatrics, Infectious Diseases and Hepatology, The Tadeusz Browicz Provincial Hospital for Infectious Diseases and Observation in Bydgoszcz, Poland
Clin Exp HEPATOL 2025; 11, 3: 228–231
Online publish date: 2025/09/04
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Benign recurrent intrahepatic cholestasis (BRIC) is a rare genetic disorder characterized by episodes of intrahepatic cholestasis with varying durations and spontaneous resolutions. This article presents the use of nasobiliary drainage (NBD) in inducing remission of BRIC in our patients. We also analyze recent studies, case reports, and systematic reviews on the topic to provide an overview of the efficacy and safety of NBD in the management of BRIC. The paper is a review of a rarely (especially in children) used technique in therapy of acute episode of BRIC with a short presentation of a small series of patients in whom such a technique was applied in a single center. Our findings suggest that NBD could be a promising and effective approach for inducing remission in BRIC patients, warranting further research and larger clinical trials to better understand its long-term impact.
keywords:

ERCP, BRIC, NBD

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