Pediatric Endocrinology Diabetes and Metabolism

Abstract

1/2026 vol. 32
Original paper

Ketoacidosis in new-onset type 1 diabetes: return to pre-COVID-19 pandemic reality?

  1. Department of Paediatrics, Unidade Local de Saúde Região de Aveiro, Portugal
  2. Paediatric Endocrinology, Diabetes and Growth Unit, Hospital Pediátrico de Coimbra, Unidade Local de Saúde de Coimbra, Portugal
  3. Department of Paediatrics, Unidade Local de Saúde do Médio Tejo, Torres Novas, Portugal
  4. Department of Paediatrics, Unidade Local de Saúde Viseu Dão-Lafões, Viseu, Portugal
Pediatr Endocrinol Diabetes Metab 2026; 32 (1): 32-37
Online publish date: 2026/03/30
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Introduction

Type 1 diabetes mellitus (T1D) is one of the most common chronic diseases in childhood, with its incidence increasing globally. The coronavirus disease 2019 (COVID-19) pandemic has been associated with an increase in severity of cases of diabetic ketoacidosis.

Aim of the study

Type 1 diabetes mellitus (T1D) is one of the most common chronic diseases in childhood, with its incidence increasing globally. The coronavirus disease 2019 (COVID-19) pandemic has been associated with an increase in severity of cases of diabetic ketoacidosis.

Material and methods

A retrospective cohort study was conducted, using patients’ clinical records, between March 2016 and March 2024. The sample was divided in three groups: pre-pandemic (March 2016 to March 2020), pandemic (March 2020 to March 2021), and post-pandemic (March 2021 to March 2024).

Results

A retrospective cohort study was conducted, using patients’ clinical records, between March 2016 and March 2024. The sample was divided in three groups: pre-pandemic (March 2016 to March 2020), pandemic (March 2020 to March 2021), and post-pandemic (March 2021 to March 2024).

Conclusions

There was an improvement in the post-pandemic period, with a lower severity at presentation. However, the rate of ketoacidosis remained high, and the focus must remain on implementing preventative measures.

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