Laugier-Hunziker syndrome – a rare cause of acquired hyperpigmentation

Mariana Karwan; Piotr Brzeziński

doi:10.5114/dr.2022.116733

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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1/2022
vol. 109

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abstract:

Case report

Laugier-Hunziker syndrome – a rare cause of acquired hyperpigmentation

Mariana Karwan

¹

,

Piotr Brzeziński

^{1, 2}

Dermatology Ward of the District Tertiary Hospital, Slupsk, Poland

Cosmetology Laboratory of the Chair of Rehabilitation and Biological Renewal, Institute of Health Sciences, Pomeranian University, Slupsk, Poland

Dermatol Rev/Przegl Dermatol 2022, 109, 52-57

DOI: https://doi.org/10.5114/dr.2022.116733

Online publish date: 2022/05/31

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Introduction
Laugier-Hunziker syndrome is a rare acquired disorder characterized by diffuse hyperapigmentation of the oral mucosa and longitudinal melanonychia in adults. Laugier-Hunziker syndrome is considered a benign disease with no systemic symptoms nor malignant potential.

Case report
In a 48-year-old women hyperpigmentation developed in the buccal mucosa, lips, labia, nail plates and the skin of fingers and toes. Laugier-Hunziker syndrome was diagnosed on the basis of clinical presentation, dermoscopy, and exclusion of systemic causes of the symptoms.

Conclusions
Laugier-Hunziker syndrome is an idiopathic hyperpigmentation of skin, oral mucosa, lips and nails and should be considered a diagnosis of exclusion.

keywords:

Laugier-Hunziker syndrome – a rare cause of acquired hyperpigmentation

Mariana Karwan 1 , Piotr Brzeziński 1, 2

Laugier-Hunziker syndrome, mucocutaneous pigmentation, oral cavity pigmentation, discolorations, oral mucosa

Mariana Karwan

¹

,

Piotr Brzeziński

^{1, 2}