Leczenie chorych na toczniowe zapalenie nerek

Andrzej Oko; Stanisław Czekalski

ISSN: 1505-8409

Przewodnik Lekarza/Guide for GPs

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5/2009
vol. 12

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abstract:

Leczenie chorych na toczniowe zapalenie nerek

Andrzej Oko

,

Stanisław Czekalski

Przew Lek 2009; 5: 51-54

Online publish date: 2009/10/05

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The metod of the treatment of lupus nephritis depends on disease activity, kidney function at presentation and on morphological type of glomerulonephritis according to WHO classification. According to these criteria, monotherapy with corticosteroids or in combination with immunosuppressive drugs, like cyclophosphamide, azathioprine, mycophenolate and cyclosporine, should be considered. The first goal of the treatment is to achieve remission using induction therapy. After remission, the treatment should be maintained with lower doses of the drugs or by the conversion to less toxic immunosuppressants. During the therapy, the potential toxicity of the drugs used must be carefully monitored, as well as nephro- and cardioprotective medications should be continued.

keywords:

Leczenie chorych na toczniowe zapalenie nerek

Andrzej Oko , Stanisław Czekalski

nephritis, secondary glomerulonephritis, immunosuppressive treatment

Andrzej Oko

,

Stanisław Czekalski