Introduction:

Lichen amyloidosis is the most common form of primary localized amyloidosis of the skin. Typical lesions are hyperpigmented and hyperkeratotic papules with a predilection for the extensor surfaces of lower extremities. Histopathology reveals amyloid material in papillary dermis.

Case report:

We present the case of a 63-year-old woman with hyperkeratotic papules located on her lower extremities with accompanying pruritus, lasting for about 10 years. She had a history of, inter alia, choledocholithiasis and liver cirrhosis. Based on the clinical, dermoscopic and histopathological presentation, the diagnosis of lichen amyloidosis was established. The patient was treated with 0.05% clobetasol propionate ointment and salicylic acid in combination with urea with improvement.

Conclusions:

Lichen amyloidosis is a rare disease with characteristic clinical, dermoscopic and histopathological findings. It may be associated with internal diseases. Treatment options are based on case reports, with no definitive recommendations of treatment available.