Livedo vasculopathy

Katarzyna Żórawicz

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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5/2012
vol. 99

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abstract:

Special paper

Livedo vasculopathy

Katarzyna Żórawicz

Przegl Dermatol 2012, 99, 587–594

Online publish date: 2012/10/27

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Livedo vasculopathy is a chronic, recurrent disease of small blood vessels, localized on the distal parts of lower extremities. It is clinically characterized by purpuric macules and papules that progress to painful ulcerations which heal leaving white-coloured, asteroid-shaped scars (atrophie blanche). The etiopathogenesis of the disease is still unclear. Thrombo-embolic or inflammatory etiology is suspected. Histopathology manifests endothelial proliferation, thrombotic occlusion and segmental hyalinosis of blood vessels. Immunopathology shows depositions of immunoglobulins, fibrin and complement in vessel walls. If clinical and histopathological features suggest the diagnosis, there is a need to carry out a screening for coagulation disorders. The optimal treatment has not been determined.

keywords:

Livedo vasculopathy

Katarzyna Żórawicz

livedo vasculitis, atrophie blanche, vasculopathy