Microneedling with topical administration of bleomycin 
as a treatment method for plantar warts

Michał Smoczok; Szymon Leonik; Beata Bergler-Czop; Katarzyna Nowak

doi:10.5114/dr.2022.116732

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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1/2022
vol. 109

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abstract:

Review article

Microneedling with topical administration of bleomycin as a treatment method for plantar warts

Michał Smoczok

¹

,

Szymon Leonik

¹

,

Beata Bergler-Czop

¹

,

Katarzyna Nowak

¹

Department of Dermatology, School of Medicine, Medical University of Silesia, Katowice, Poland
Katedra i Klinika Dermatologii, Wydział Nauk Medycznych, Śląski Uniwersytet Medyczny, Katowice, Polska

Dermatol Rev/Przegl Dermatol 2022, 109, 43-51

DOI: https://doi.org/10.5114/dr.2022.116732

Online publish date: 2022/05/31

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Plantar warts are a viral disease caused by a broad spectrum of HPV viruses (in particular HPV 1, 2, 27 and 57), with a frequency of 7–14% in the general population. Bleomycin, a cytostatic used in the treatment of plantar warts, shows variable efficacy in the conducted studies (16–97% cure rate), depending on the concentration used and the method of administration of the drug. One of the methods of increasing the efficacy of bleomycin is the use of microneedling, a procedure that creates a series of channels to improve penetration of the substance. It has shown an improvement in the response time to bleomycin treatment of plantar warts, as well as a reduction in the number of treatment sessions required. The rate of relapse using this method is similar to that of other injection-based methods.

keywords:

Microneedling with topical administration of bleomycin as a treatment method for plantar warts

Michał Smoczok 1 , Szymon Leonik 1 , Beata Bergler-Czop 1 , Katarzyna Nowak 1

bleomycin, warts, intralesional

Michał Smoczok

¹

,

Szymon Leonik

¹

,

Beata Bergler-Czop

¹

,

Katarzyna Nowak

¹