eISSN: 2300-6722
ISSN: 1899-1874
Medical Studies/Studia Medyczne
Current issue Archive About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
 
3/2020
vol. 36
 
Share:
Share:
more
 
 
abstract:
Review paper

Mikulicz’s disease and Sjögren’s syndrome as the main autoimmune disorders involving salivary glands

Bartłomiej Kamiński
1

1.
Otolaryngology Ward, Maria Sklodowska-Curie District Hospital, Skarżysko-Kamienna, Poland Head of the Ward: Bartłomiej Kamiński MD, PhD
Medical Studies/Studia Medyczne 2020; 36 (3): 211–218
Online publish date: 2020/09/30
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Mikulicz’s disease and Sjögren’s syndrome involve salivary glands. They are characterised by lymphocytic infiltrations in affected exocrine glands leading to their swelling and dysfunction. Although they present similar clinical symptoms, currently they belong to different classifications and require different multidisciplinary treatments. This study presents and compares Sjögren’s syndrome and Mikulicz’s disease and reviews their main clinical, histopathological, and serologic criteria and the methods used in the diagnostic process. The most reliable diagnostic method is histopathologic examination of glandular tissue obtained by either minor or major salivary gland biopsies. Serologic criteria play an additional diagnostic role. The different radiological modalities allow the exclusion of other inflammatory and neoplastic processes that can mimic the initial stages of Mikulicz’s disease and Sjögren’s syndrome.
keywords:

Mikulicz’s disease, Sjögren’s syndrome, IgG4-related diseases

Quick links
© 2021 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe