Abstract
5/2003
vol. 11
Consequences of parvovirus B19 infection in women with imminent abortion
Gin Prakt 2003, 11, 5, 48-51
Online publish date: 2003/10/16
Purpose of the study was to determine serologic or genetic markers of parvovirus B19 infection (PV-B19) in women during first trimester of pregnancy and to observe the course of infection and its influence on fetus.
IgM and IgG antibodies against PV-B19 were determined with immunoenzimatic method (BIOMEDICA). The PV-B19 DNA was detected with PCR method and obtained DNA was analyzed with Digene Sharp Signal system.
Our studies shown that abortion frequency in women with PV-B19 infection is 27%, most of them occurred during first trimester of pregnancy. Parvovirus infection in observed pregnant women was in most cases asymptomatic, therefore it may be helpful to diagnose patients towards PV-B19 infection during pregnancy.
IgM and IgG antibodies against PV-B19 were determined with immunoenzimatic method (BIOMEDICA). The PV-B19 DNA was detected with PCR method and obtained DNA was analyzed with Digene Sharp Signal system.
Our studies shown that abortion frequency in women with PV-B19 infection is 27%, most of them occurred during first trimester of pregnancy. Parvovirus infection in observed pregnant women was in most cases asymptomatic, therefore it may be helpful to diagnose patients towards PV-B19 infection during pregnancy.
Keywords
pregnancy, imminent abortion, Parvovirus B19, ELISA, PCR
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