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ISSN: 1505-8409
Przewodnik Lekarza/Guide for GPs
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3/2008
vol. 11
 
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abstract:

Obesity and cardiometabolic risk

Anna Psurek
,
Aleksandra Szymborska-Kajanek
,
Marta Wróbel
,
Krzysztof Strojek

Przew Lek 2008; 3: 10-17
Online publish date: 2008/07/11
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The prevalence of obesity has increased dramatically in recent years. The association between abdominal fat distribution and cardiometabolic syndrome has been proved in many studies. Cardiometabolic syndrome is associated with a number of cardiovascular risk factors that contribute to a high rate of vascular events, which are now the most common cause of death. Operational definitions of metabolic syndrome have been changed several times, with a tendency to emphasize the importance of central adiposity. Adipose tissue is now known to secrete a number of pro-inflammatory agents that are thought to mediate the link between obesity, insulin resistance, hyperlipidaemia, and atherosclerosis. The aim of this article is to correlate data in this area, highlighting the central role of excess visceral fat and its secreted adipokines, and to review existing therapies.
keywords:

obesity, metabolic syndrome, cardiometabolic risk, cardiovascular risk, diabetes mellitus

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