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ISSN: 1505-8409
Przewodnik Lekarza/Guide for GPs
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3/2005
vol. 8
 
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abstract:

Oral diabetic therapy in type 2 diabetes mellitus

Mariusz Jasik
,
Krzysztof Dęmbe
,
Waldemar Karnafel

Przew Lek 2005; 3: 74-80
Online publish date: 2005/05/05
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The aim of article is to review the various therapeutic agents available for management of patients with type 2 diabetes and to suggest an approach to drug selection as monotherapy and in combination theraphy. There are now five classes of oral medications which are available in therapy of type 2 diabetes – sulfonylureas, glinides, biguanides, thiazolidinediones and alpha-glucosidase inhibitors. Each class of drugs works differently to treat impaired insulin secretion, insulin resistance and postprandial hyperglycemia. Application of the strategies and principles of oral diabetic therapy in type 2 diabetes should be individualised based on the degree of hyperglycemia, hyperinsulinemia or insulin deficiency.
keywords:

type 2 diabetes mellitus, pharmacologic therapy

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