eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
Current issue Archive Manuscripts accepted About the journal Editorial board Journal's reviewers Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank
4/2009
vol. 26
 
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abstract:

Original paper
Primary skin cancers – results of photodynamic therapy

Jan Rykała
,
Cezary Peszyński-Drews
,
Henryk Witmanowski
,
Julia Kruk-Jeromin

Post Dermatol Alergol 2009; XXVI, 4: 194–196
Online publish date: 2009/08/30
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Photodynamic diagnosis and therapy of tumours is a new procedure utilizing the combined action of light and a photosensitizing drug. The laser-fibre optic delivery system allows the visualization and treatment of superficial and deeply located neoplasms including malignancies of the skin, head and neck, oesophagus, endobronchial tract, stomach, urinary bladder, female genital tract and other sites. The putative action mechanism depends on evocation of fluorescence of a photosensitizing drug within cancer tissue (important for non-invasive optical diagnosis) and involves photochemical destruction of tumour tissue membranes mediated by singlet molecular oxygen (important for destruction of tumour cells).
keywords:

skin cancers, photodynamic therapy (PDT), aminolevulinic acid (ALA)

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