Paranoid schizophrenia – gender differences in the course of the disease

Michał Wroński; Paweł Liśkiewicz; Jerzy Samochowiec

doi:10.5114/psychs.2023.124651

ISSN: 2720-7048

Psychiatria Spersonalizowana

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1/2023
vol. 2

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abstract:

Original article

Paranoid schizophrenia – gender differences in the course of the disease

Michał Wroński

¹

,

Paweł Liśkiewicz

¹

,

Jerzy Samochowiec

¹

Katedra i Klinika Psychiatrii, Pomorski Uniwersytet Medyczny w Szczecinie

DOI: https://doi.org/10.5114/psychs.2023.124651

Online publish date: 2023/01/30

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Paranoid schizophrenia is the subject of research around the world. Gender differences in the course of schizophrenia were already observed in the 1980s. Compared to female patients, who tended to report fewer adverse effects of pharmacological treatment, men were found to suffer from earlier onset schizophrenia and exhibit a poorer response to administered medications, which thus contributed to an overall less favorable prognosis. Male patients were also demonstrated to suffer from a greater manifestation of negative symptoms, including not only affective bluntness, apathy, impaired activity or social isolation, but also disorientation, impaired concentration or memory deficits. This study results, conducted on a Polish population of patients with paranoid schizophrenia, confirm the earlier reports on the differences in the course of schizophrenia in men and women.

keywords:

Paranoid schizophrenia – gender differences in the course of the disease

Michał Wroński 1 , Paweł Liśkiewicz 1 , Jerzy Samochowiec 1

schizophrenia, men, women, differences, course, Polish population

Michał Wroński

¹

,

Paweł Liśkiewicz

¹

,

Jerzy Samochowiec

¹