Pathogenetic mechanism of chronic pancreatitis

Leszek Zalewski

ISSN: 1505-8409

Przewodnik Lekarza/Guide for GPs

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3/2005
vol. 8

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abstract:

Pathogenetic mechanism of chronic pancreatitis

Leszek Zalewski

Przew Lek 2005; 3: 120-124

Online publish date: 2005/05/05

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Chronic pancreatitis is a disease of the heterogenous etiology. Chronic pancreatitis insufficiency is the most commonly caused by chronic alcohol abuse.
The mechanism by which ethanol abuse and the other etiologic factors results in chronic destructive changes in the pancreas is unknown. A new classification system (TIGAR-O) proposes risk modifiers – not etiologies – that may interact in any one patient to produce pancreatic disease. Each of the listed risk factors may predispose toward pancreatitis through different pathogenetic mechanism.

keywords:

Pathogenetic mechanism of chronic pancreatitis

Leszek Zalewski

chronic pancreatitis, pathogenesis