Abstract
2/2011
vol. 10
Genetic background of hearing impairment – Poznan experience
(Postępy w Chirurgii Głowy i Szyi 2011; 2: 17–23)
Online publish date: 2011/10/18
There are more than 80 genes associated with sensorineural hearing loss identified and described in the literature. Among them, GJB2 gene with mutation 35delG and mitochondrial gene 12SrRNA with mutation A1555G are recognized to be the most frequent and important in the aetiology of congenital non-syndromic hearing loss and hearing impairment related to aminoglycosides treatment. This review presents data and outcomes on studies conducted at the Otolaryngology and Oncological Laryngology Department at Poznan University of Medical Sciences.
Keywords
non-syndromic hearing loss, genetic factor, DNA mutation, molecular diagnostic
Coverage in
Integrated with
