eISSN: 2449-8238
ISSN: 2392-1099
Clinical and Experimental Hepatology
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SCImago Journal & Country Rank
2/2019
vol. 5
 
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abstract:
Original paper

Prevalence of hepatitis C virus infection in patients hospitalised for ischemic heart disease versus controls – PRO-CARDIO-C study

Anna Piekarska
,
Aleksandra Mamzer-Dachnowska
,
Jarosław D. Kasprzak
,
Jan Z. Peruga
,
Andrzej Kaszuba
,
Aleksandra Berkan-Kawińska

Clin Exp HEPATOL 2019; 5, 2: 118–122
Online publish date: 2019/05/08
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Aim of the study
Ongoing national screening programmes suggest that the prevalence of chronic hepatitis C (CHC) in Poland ranges between 0.5% and 1%. It has been recently noted that patients with confirmed coronary artery disease may be at higher risk for hepatitis C virus (HCV) infection.

Material and methods
Testing for the presence of anti-HCV antibodies was performed in a group of patients admitted to the Cardiology Department with symptomatic ischemic heart disease (IHD) and in patients hospitalised in the Dermatology Department.

Results
A total of 1171 patients underwent anti-HCV testing: 672 patients in the Cardiology Department (K group) and 499 patients in the Dermatology Department (D group). Twenty-eight (2.4%) positive anti-HCV results were detected. The prevalence of positive anti-HCV antibodies in groups K and D was 2.23% and 2.61%, respectively (p > 0.05). Presence of HCV RNA was confirmed in 15 cases (1.28%) – 7 patients in group K and 8 patients in group D (1.04% and 1.6%, respectively; p > 0.05).

Conclusions
Our findings suggest that this patient cohort has increased risk of HCV infection, which may influence screening strategies.

keywords:

hepatitis C, coronary artery disease, anti-HCV antibody, screening, HCV treatment

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