Primary Cutaneous Anaplastic Large T-Cell Lymphoma

Magdalena Justyna Kacperska-Olborska; Jerzy Ogłuszka; Bogusław Olborski; Monika Grochowska-Rak

doi:10.5114/dr.2025.155985

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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4/2025
vol. 112

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abstract:

Case report

Primary Cutaneous Anaplastic Large T-Cell Lymphoma

Magdalena Justyna Kacperska-Olborska

¹

,

Jerzy Ogłuszka

²

,

Bogusław Olborski

³

,

Monika Grochowska-Rak

⁴

Patomorphology Department, John Paul II Provincial Hospital, Belchatow
Oncological Surgery Outpatient Clinic, John Paul II Provincial Hospital, Belchatow
Diagnostyka Consilio, Lodz, Poland
Department of Dermatology, John Paul II Provincial Hospital, Belchatow

Dermatol Rev/Przegl Dermatol 2025, 112, 253–257

DOI: https://doi.org/10.5114/dr.2025.155985

Online publish date: 2025/10/30

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Introduction
Anaplastic large cell lymphoma is a rare entity belonging to CD30+ lymphoproliferative disease classified as T- and NK-cell lymphoid disorders and neoplasms. Primary cutaneous lymphomas are confined to the skin, without involvement of lymph nodes or internal organs. Symptoms such as pruritus, fatigue, and cutaneous lesions are often misdiagnosed as allergic reactions or psoriasis.

Objective
To present a case of primary cutaneous anaplastic large cell lymphoma and highlight the diagnostic challenges associated with this condition.

Case report
A patient with long-standing cutaneous lesions, initially treated dermatologically, was referred to oncology clinic. Histopathological examination of the skin and lymph node biopsies confirmed the diagnosis of primary cutaneous CD30+ lymphoproliferative disorder clinically corresponding to anaplastic large cell lymphoma. Oncology-directed treatment was initiated.

Conclusions
Cutaneous lymphomas are challenging to diagnose. Histopathological assessment is crucial for accurate identification. Early diagnosis and prompt treatment significantly improve prognosis.

keywords:

lymphatic system, cutaneous T-cell lymphoma, primary cutaneous lymphoma, anaplastic cells, primary cutaneous anaplastic large T-cell lymphoma

Indeks osobowy

Primary Cutaneous Anaplastic Large T-Cell Lymphoma

Magdalena Justyna Kacperska-Olborska 1 , Jerzy Ogłuszka 2 , Bogusław Olborski 3 , Monika Grochowska-Rak 4

lymphatic system, cutaneous T-cell lymphoma, primary cutaneous lymphoma, anaplastic cells, primary cutaneous anaplastic large T-cell lymphoma

Magdalena Justyna Kacperska-Olborska

¹

,

Jerzy Ogłuszka

²

,

Bogusław Olborski

³

,

Monika Grochowska-Rak

⁴