Primary cutaneous anaplastic large-cell lymphoma in a patient with Hodgkin’s disease – case report

Introduction. Cutaneous anaplastic large cell lymphoma (C-ALCL) is one of the CD30+ lymphoproliferative disorders. Usually it has a mild course and does not require aggressive treatment. The prognosis in

C-ALCL is good, with the 10-year survival rate reaching 90% of patients. Spontaneous remissions of the disease are possible.

Objective. To present a patient with recurrent Hodgkin’s disease, in whom primary cutaneous anaplastic large cell lymphoma was diagnosed.

Case report. A 35-year old woman with recurrent Hodgkin’s disease was admitted to the department for diagnosis and treatment of skin lesions, which appeared a few weeks ago. Primary cutaneous T-cell lymphoma was diagnosed by histopathology and immunohistochemistry. After two weeks spontaneous regression of skin lesions was observed.

Conclusions. Larger diagnostic procedures and exclusion of the systemic form of ALCL, cutaneous metastases of Hodgkin’s disease and large-cell transformation of mycosis fungoides are required due to the aggressive course and different treatment in all cases.