Psoriasis in the paediatric population: assessment
of comorbidities, risk factors of their occurrence, quality
of life of patients and therapy implemented

Magdalena Szczegielniak; Aleksandra Lesiak; Kamil Grabowski; Adam Reich; Aleksandra Opalińska; Hubert Arasiewicz; Joanna Narbutt

doi:10.5114/ada.2025.155415

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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5/2025
vol. 42

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abstract:

Original paper

Psoriasis in the paediatric population: assessment of comorbidities, risk factors of their occurrence, quality of life of patients and therapy implemented

Magdalena Szczegielniak

¹

,

Aleksandra Lesiak

¹

,

Kamil Grabowski

¹

,

Adam Reich

²

,

Aleksandra Opalińska

²

,

Hubert Arasiewicz

³

,

Joanna Narbutt

¹

Department of Dermatology, Paediatric Dermatology and Oncology, Medical University of Lodz, Poland
Department of Dermatology, Fryderyk Chopin Provincial Hospital No. 1, University of Rzeszow, Poland
Dermatology Unit, John Paul II Paediatrics Center, Sosnowiec, Poland

Adv Dermatol Allergol 2025; XLII (5): 467–474

DOI: https://doi.org/10.5114/ada.2025.155415

Online publish date: 2025/10/20

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EndNote

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AMA

Szczegielniak M, Lesiak A, Grabowski K, et al. Psoriasis in the paediatric population: assessment
of comorbidities, risk factors of their occurrence, quality
of life of patients and therapy implemented. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2025;42(5):467-474. doi:10.5114/ada.2025.155415.

APA

Szczegielniak, M., Lesiak, A., Grabowski, K., Reich, A., Opalińska, A.,  & Arasiewicz, H. et al. (2025). Psoriasis in the paediatric population: assessment
of comorbidities, risk factors of their occurrence, quality
of life of patients and therapy implemented. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 42(5), 467-474. https://doi.org/10.5114/ada.2025.155415

Chicago

Szczegielniak, Magdalena, Aleksandra Lesiak, Kamil Grabowski, Adam Reich, Aleksandra Opalińska, Hubert Arasiewicz,  and Joanna Narbutt. 2025. "Psoriasis in the paediatric population: assessment
of comorbidities, risk factors of their occurrence, quality
of life of patients and therapy implemented". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 42 (5): 467-474. doi:10.5114/ada.2025.155415.

Harvard

Szczegielniak, M., Lesiak, A., Grabowski, K., Reich, A., Opalińska, A., Arasiewicz, H.,  and Narbutt, J. (2025). Psoriasis in the paediatric population: assessment
of comorbidities, risk factors of their occurrence, quality
of life of patients and therapy implemented. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 42(5), pp.467-474. https://doi.org/10.5114/ada.2025.155415

MLA

Szczegielniak, Magdalena et al. "Psoriasis in the paediatric population: assessment
of comorbidities, risk factors of their occurrence, quality
of life of patients and therapy implemented." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 42, no. 5, 2025, pp. 467-474. doi:10.5114/ada.2025.155415.

Vancouver

Szczegielniak M, Lesiak A, Grabowski K, Reich A, Opalińska A, Arasiewicz H et al. Psoriasis in the paediatric population: assessment
of comorbidities, risk factors of their occurrence, quality
of life of patients and therapy implemented. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2025;42(5):467-474. doi:10.5114/ada.2025.155415.

Introduction
Psoriasis is caused by a systemic inflammatory process. In the adult population, it may be concomitant with many diseases, especially cardiovascular ones and metabolic disorders. The incidence of psoriasis-related comorbidities in children and adolescents is subjected to in clinical trials.

Aim
The analysis of cases of children diagnosed with psoriasis depending on sex, age and medical history data, determination of the frequency of comorbidities and their risk factors, assessment of the quality of life of the patients and their families, educating the patients about psoriasis, collecting data on the methods of psoriasis treatment in the paediatric population.

Material and methods
The study included 99 children with psoriasis (61 girls and 38 boys), hospitalized in 3 paediatric dermatology centres from March 2020 to March 2022.

Results
The Psoriasis Area and Severity Index (PASI) score ≥ 10, indicating moderate and severe psoriasis, was obtained in 56% of the subjects, while the PASI score < 10, indicating mild psoriasis, was obtained in 44% of the subjects. Body mass index (BMI) above the reference range for age and sex was found in 19% of the patients. Comorbidities other than obesity were observed in 27% of the patients. Laboratory tests revealed lipid disorders and other deviations that might indicate chronic diseases.

Conclusions
Psoriatic children and adolescents are often obese and with abnormal lipid profile, which may constitute a risk factor of cardiovascular diseases. Psoriasis has a negative impact on the quality of life of patients and their families.

keywords:

Psoriasis in the paediatric population: assessment of comorbidities, risk factors of their occurrence, quality of life of patients and therapy implemented

Magdalena Szczegielniak 1 , Aleksandra Lesiak 1 , Kamil Grabowski 1 , Adam Reich 2 , Aleksandra Opalińska 2 , Hubert Arasiewicz 3 , Joanna Narbutt 1

paediatric psoriasis, metabolic syndrome, comorbidities

Magdalena Szczegielniak

¹

,

Aleksandra Lesiak

¹

,

Kamil Grabowski

¹

,

Adam Reich

²

,

Aleksandra Opalińska

²

,

Hubert Arasiewicz

³

,

Joanna Narbutt

¹