Family Medicine & Primary Care Review
eISSN: 2449-8580
ISSN: 1734-3402
Family Medicine & Primary Care Review
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SCImago Journal & Country Rank
4/2025
vol. 27
 
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abstract:

Pulmonary function test in children: Multiple Breath Washout (MBW) – a position statement of the Polish Society of Pediatric Pulmonology (STAN PNEUMO: MBW)

Katarzyna Walicka-Serzysko
1, 2
,
Magdalena Postek
1, 2
,
Eliza Wasilewska
3, 4
,
Joanna Peradzyńska
5
,
Katarzyna Krenke
6
,
Zbigniew Doniec
7, 8
,
Irena Wojsyk-Banaszak
9

  1. Cystic Fibrosis Department, Institute of Mother and Child, Warsaw, Poland
  2. Cystic Fibrosis Centre, Pediatric Hospital, Dziekanow Lesny, Poland
  3. Department of Allergology, Medical University of Gdansk, Gdansk, Poland
  4. Laboratory of Lung Function Testing for Children and Adolescents, University Clinical Centre in Gdansk, Gdansk, Poland
  5. Department of Epidemiology and Biostatistics, Medical University of Warsaw, Warsaw, Poland
  6. Department of Pediatric Pulmonology and Allergology, Medical University of Warsaw, Warsaw, Poland
  7. Department of Respiratory System Physiotherapy, Institute of Tuberculosis and Lung Disease Field Branch in Rabka-Zdroj, Rabka-Zdroj, Poland
  8. Institute of Medicine, Academy of Applied Science in Nowy Targ, Nowy Targ, Poland
  9. Department of Pulmonology, Pediatric Allergy and Clinical Immunology, Poznan University of Medical Sciences, Poznan, Poland
Family Medicine & Primary Care Review 2025; 27(4)
Online publish date: 2025/12/22
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The multiple breath washout (MBW) test is a highly sensitive method for detecting early abnormalities in pulmonary function through the assessment of ventilation distribution. As it does not rely on forced respiratory maneuvers, MBW can be successfully performed in young children and individuals with limited ability to cooperate. This technique is particularly valuable in identifying both early, reversible changes caused by localized inflammation and mucus retention, as well as irreversible structural damage resulting from fibrosis and progressive destruction of the lung parenchyma in peripheral airway diseases.

The growing availability of commercial MBW devices has facilitated its adoption in clinical research and contributed to its increasing integration into routine clinical practice. This position statement by the Polish Society of Pediatric Pulmonology outlines the technical aspects of the MBW procedure, guidance for interpreting test results, and potential clinical applications.
keywords:

respiratory function tests, pulmonary medicine, child

 
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