eISSN: 1897-4309
ISSN: 1428-2526
Contemporary Oncology/Współczesna Onkologia
Current issue Archive Contemporary Oncology
1A/2015
 
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abstract:

Review
The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge

Katarzyna Tomczak
,
Patrycja Czerwińska
,
Maciej Wiznerowicz

Contemp Oncol (Pozn) 2015; 19 (1A): A68–A77
Online publish date: 2015/01/20
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The Cancer Genome Atlas (TCGA) is a public funded project that aims to catalogue and discover major cancer-causing genomic alterations to create a comprehensive “atlas” of cancer genomic profiles. So far, TCGA researchers have analysed large cohorts of over 30 human tumours through large-scale genome sequencing and integrated multi-dimensional analyses. Studies of individual cancer types, as well as comprehensive pan-cancer analyses have extended current knowledge of tumorigenesis. A major goal of the project was to provide publicly available datasets to help improve diagnostic methods, treatment standards, and finally to prevent cancer. This review discusses the current status of TCGA Research Network structure, purpose, and achievements.
keywords:

The Cancer Genome Atlas (TCGA), cancer genomics, big data analysis

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