eISSN: 2084-9834
ISSN: 0034-6233
Reumatologia/Rheumatology
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2/2006
vol. 44
 
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abstract:

Review paper
Digestive tract in patients with systemic sclerosis

Grzegorz Pulkowski
,
Jacek Budzyński
,
Maria Kłopocka
,
Maciej Świątkowski

Ru 2006; 44, 2: 95-101
Online publish date: 2006/04/28
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Digestive tract is the most common internal organ involved in systemic sclerosis. This process may concern each part of alimentary system, and most frequently consist on motility disturbances or mucosal changes (teleangiectases, protein-losing gastroenteropathy). Their complications are: gastroesophageal reflux, slowdown of oesophago- gastro- intestinal transit, malabsorption syndrome with complicated pathogenesis, and serious hemorrhages. Autoimmunological disorders accompanying scleroderma favor coexistence with celiac disease, Crohn disease and primary biliary cirrhosis. Treatment of symptoms originated from digestive tract in patients with systemic sclerosis include: dietary advices, pharmacotherapy with prokinetics, antibiotics, cholestyramine, and pancreatic enzymes substitution, as well as endoscopic therapy and surgery.
keywords:

scleroderma, digestive tract, oesophagus, stomach, intestine, liver, pancreas







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