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eISSN: 2084-9877
ISSN: 1896-9666
Przegląd Kardiodiabetologiczny/Cardio-Diabetological Review
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2/2009
vol. 4
 
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abstract:

Review paper
Dysfunction of carbohydrate metabolism in primary hyperaldosteronism and hyperprolactinaemia

Małgorzata Frąckiel
,
Małgorzata Szelachowska

Przegląd Kardiodiabetologiczny 2009; 4, 2: 83–86
Online publish date: 2009/08/07
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In endocrinopathy usually we can observe hyperinsulinism and impaired glucose tolerance, mostly without acidosis. Increased secretion of hormones antagonistic to insulin induces metabolic dysfunction, for example increasing the production of glucose in the liver, by intensifying glycogenolysis and gluconeogenesis, as well as decreasing its use in peripheral tissue. In this case we observe: hyperglycaemia and impaired glucose tolerance. The increased insulin secretion is responsible for tissue resistance and stimulation by hormones antagonistic to insulin.
keywords:

primary hyperaldosteronism, hyperprolactinaemia, diabetes mellitus type 1, diabetes mellitus type 2

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