Termedia.pl
 
 
ISSN: 1505-8409
Przewodnik Lekarza/Guide for GPs
Current issue Archive About the journal Supplements Contact Instructions for authors
3/2005
vol. 8
 
Share:
Share:
more
 
 
abstract:

Risk factors of cardiovascular disease in patients with diabetes mellitus type 2Przew Lek 2005; 3: 46-52

Przemysław Krasnodębski

Przew Lek 2005; 3: 46-52
Online publish date: 2005/05/05
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Cardiovascular disease is the main cause of increased mortality in diabetes patients. Myocardial infraction and stroke is in 60 to 80% causes reason of death in patients with type 2 diabetes mellitus. The main risk factors of cardiovascular disease are: hyperglycaemia, hyperinsulinaemia, insulin resistance, dyslipidaemia and hypertension. The other atherosclerosis risk factors are: smoking; increased levels of homocystein, C-reactive protein and fibrinogen. The key pathogenetic mechanism of diabetic vascular complications is increased oxidative stress due to chronic hiperglycaemia. Oxygen-derived free radicals cause lipoprotein oxidation, endothelial dysfunction, platelets hiperreactivity and blood clotting disorders. Determination of the role of this risk factors in patogenesis of diabetic angiopathy may be of significant importance in their effective therapy.
keywords:

diabetes mellitus, hyperglycaemia, oxidative stres, dyslipidaemia

Quick links
© 2022 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.