Role of hematopoetic growth factors in the treatment of neutropenia caused by chemotherapy and radiotherapy of cancer

Janusz Skowronek

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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4/1999
vol. 3

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abstract:

Role of hematopoetic growth factors in the treatment of neutropenia caused by chemotherapy and radiotherapy of cancer

Janusz Skowronek

Współcz Onkol (1999) 4, 152-153

Online publish date: 2003/08/05

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Granulocyte, macrophage colony stimulating factor (GM-CSF) is one of the well recognised cytokines involved in the regulation of hematopoiesis. GM-CSF has demonstrated efficacy in decreasing the duration of neutropenia, decreasing the attendant infection, and enhancing the ability to deliver full doses of myelosuppressive therapy and continuation of radiotherapy. GM-CSF can also reverse the neutropenia of myelodysplastic syndrome and aplastic anemia.

In this paper the GM-CSF and possibilities of its application in the treatment of neutropenia inducted by chemotherapy and radiotherapy and in the treatment of some diseases of the hematopoietic system are presented.

keywords:

Role of hematopoetic growth factors in the treatment of neutropenia caused by chemotherapy and radiotherapy of cancer

Janusz Skowronek

GM-CSF, molgramostin, neutropenia, chemotherapy, radiotherapy