Full text
3/2026
vol. 32
Case report
Severe adrenal insufficiency coexisting with autoimmune thyroiditis (Schmidt’s syndrome) – case report
nstitute of Paediatrics, Department of Paediatric Endocrinology and Rheumatology, Poznan University
of Medical Sciences, Poland
Pediatr Endocrinol Diabetes Metab 2026; 32 (3): 230-233
Data publikacji online: 2026/09/14
- Wang X, Ping F, Qi C, et al. Delayed diagnosis with autoimmune polyglandular syndrome type 2 causing acute adrenal crisis: a case report. Medicine (Baltimore) 2016; 95: e5062. doi:10.1097/MD.0000000000005062.
- Klenczar K, Deja G, Kalina-Faska B, Jarosz-Chobot P. Miastenia, choroba Gravesa-Basedowa i inne zaburzenia autoimmunizacyjne u pacjentki z cukrzycą typu 1 – prezentacja przypadku APS-3, trudności terapeutyczne [Myasthenia gravis, Graves-Basedow disease and other autoimmune diseases in patient with diabetes type 1 – APS-3 case report, therapeutic complications]. Pediatr Endocrinol Diabetes Metab 2017; 23: 159–164. doi: 10.18544/PEDM-23.03.0088.
- Martins SC, Venade G, Teixeira M, et al. Autoimmune polyglan-dular syndrome type 2. Rev Assoc Med Bras (1992) 2019; 65: 1434–1437. doi: 10.1590/1806‑9282.65.12.1434.
- Kirkgoz T, Guran T. Primary adrenal insufficiency in children: diagnosis and management. Best Pract Res Clin Endocrinol Metab 2018; 32: 397–424. doi: 10.1016/j.beem.2018.05.010.
- Betterle C, Lazzarotto F, Presotto F. Autoimmune polyglandular syndrome type 2: the tip of an iceberg? Clin Exp Immunol 2004; 137: 225–233. doi: 10.1111/j.1365‑2249.2004.02561.x.
- Arrigoni M, Cavarzere P, Nicolussi Principe L, et al. Autoimmune adrenal insufficiency in children: a hint for polyglandular syndrome type 2? Ital J Pediatr 2023; 49: 94. doi: 10.1186/s13052‑023‑01502‑y.
- Schulz L, Hammer E. Autoimmune polyglandular syndrome type II with co-manifestation of Addison’s and Graves’ disease in a 15-year-old boy: case report and literature review. J Pediatr Endocrinol Metab 2020; 33: 575–578. doi:10.1515/jpem-2019-0417.
- Smith RK, Gerrits PM. A rare case of autoimmune polyglandular syndrome type 2 in a child with persistent fatigue. Glob Pediatr Health 2019; 6: 2333794X19845056. doi: 10.1177/2333794X19845056.
- Mourinho Bala N, Gonçalves RS, Serra Caetano J, et al. Autoimmune primary adrenal insufficiency in children. J Clin Res Pediatr Endocrinol 2022; 14: 308–312. doi: 10.4274/jcrpe.galenos.2021.2021-9-7.
- Bonataki M, Dikaiakou E, Anastasopoulou P, et al. An 11-year-old girl with autoimmune polyglandular syndrome (APS) type 2: a case report and review of literature. J Pediatr Endocrinol Metab 2023; 36: 508–512. doi: 10.1515/jpem-2022-0619.


