Pediatric Endocrinology Diabetes and Metabolism

Full text

3/2026 vol. 32
Case report

Severe adrenal insufficiency coexisting with autoimmune thyroiditis (Schmidt’s syndrome) – case report

  1. nstitute of Paediatrics, Department of Paediatric Endocrinology and Rheumatology, Poznan University
    of Medical Sciences, Poland

Pediatr Endocrinol Diabetes Metab 2026; 32 (3): 230-233

Data publikacji online: 2026/09/14
Article file
0407_Severe adrenal.pdf
Confronting perimenopausal women’s knowledge of coronary heart disease with their health behaviours. Controversial role of hormone replacement therapy in the protection of coronary heart disease
  1. Wang X, Ping F, Qi C, et al. Delayed diagnosis with autoimmune polyglandular syndrome type 2 causing acute adrenal crisis: a case report. Medicine (Baltimore) 2016; 95: e5062. doi:10.1097/MD.0000000000005062.
  2. Klenczar K, Deja G, Kalina-Faska B, Jarosz-Chobot P. Miastenia, choroba Gravesa-Basedowa i inne zaburzenia autoimmunizacyjne u pacjentki z cukrzycą typu 1 – prezentacja przypadku APS-3, trudności terapeutyczne [Myasthenia gravis, Graves-Basedow disease and other autoimmune diseases in patient with diabetes type 1 – APS-3 case report, therapeutic complications]. Pediatr Endocrinol Diabetes Metab 2017; 23: 159–164. doi: 10.18544/PEDM-23.03.0088.
  3. Martins SC, Venade G, Teixeira M, et al. Autoimmune polyglan-dular syndrome type 2. Rev Assoc Med Bras (1992) 2019; 65: 1434–1437. doi: 10.1590/1806‑9282.65.12.1434.
  4. Kirkgoz T, Guran T. Primary adrenal insufficiency in children: diagnosis and management. Best Pract Res Clin Endocrinol Metab 2018; 32: 397–424. doi: 10.1016/j.beem.2018.05.010.
  5. Betterle C, Lazzarotto F, Presotto F. Autoimmune polyglandular syndrome type 2: the tip of an iceberg? Clin Exp Immunol 2004; 137: 225–233. doi: 10.1111/j.1365‑2249.2004.02561.x.
  6. Arrigoni M, Cavarzere P, Nicolussi Principe L, et al. Autoimmune adrenal insufficiency in children: a hint for polyglandular syndrome type 2? Ital J Pediatr 2023; 49: 94. doi: 10.1186/s13052‑023‑01502‑y.
  7. Schulz L, Hammer E. Autoimmune polyglandular syndrome type II with co-manifestation of Addison’s and Graves’ disease in a 15-year-old boy: case report and literature review. J Pediatr Endocrinol Metab 2020; 33: 575–578. doi:10.1515/jpem-2019-0417.
  8. Smith RK, Gerrits PM. A rare case of autoimmune polyglandular syndrome type 2 in a child with persistent fatigue. Glob Pediatr Health 2019; 6: 2333794X19845056. doi: 10.1177/2333794X19845056.
  9. Mourinho Bala N, Gonçalves RS, Serra Caetano J, et al. Autoimmune primary adrenal insufficiency in children. J Clin Res Pediatr Endocrinol 2022; 14: 308–312. doi: 10.4274/jcrpe.galenos.2021.2021-9-7.
  10. Bonataki M, Dikaiakou E, Anastasopoulou P, et al. An 11-year-old girl with autoimmune polyglandular syndrome (APS) type 2: a case report and review of literature. J Pediatr Endocrinol Metab 2023; 36: 508–512. doi: 10.1515/jpem-2022-0619.
Share
without publication fees