Standards of nasal provocation tests

Bolesław Samoliński; Piotr Rapiejko; Edyta Krzych-Fałta; Tomasz Gotlib; Andrzej Emeryk; Krzysztof Buczyłko; Marta Chełmińska; Konrad Chełmiński; Marek Niedoszytko; Monika Świerczyńska-Kępa; Maciej Kupczyk; Adam Sybilsk; Henryk Mazurek; Radosław Gawlik; Marek Modrzyński; Ewa Niżankowska-Mogilnicka; Piotr Kuna; Andrzej Szczeklik; Cezary Pałczyński

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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3/2010
vol. 27

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abstract:

Standards of nasal provocation tests

Bolesław Samoliński

,

Piotr Rapiejko

,

Edyta Krzych-Fałta

,

Tomasz Gotlib

,

Andrzej Emeryk

,

Krzysztof Buczyłko

,

Marta Chełmińska

,

Konrad Chełmiński

,

Marek Niedoszytko

,

Monika Świerczyńska-Kępa

,

Maciej Kupczyk

,

Adam Sybilsk

,

Henryk Mazurek

,

Radosław Gawlik

,

Marek Modrzyński

,

Ewa Niżankowska-Mogilnicka

,

Piotr Kuna

,

Andrzej Szczeklik

,

Cezary Pałczyński

Post Dermatol Alergol 2010; XXVII, 3: 149–161

Online publish date: 2010/07/05

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The nasal allergen provocation test (NAPT) plays an important role in diagnosis of allergy. It is based on the natural reaction of the nasal mucosa after application of tested substances on their surface. Nasal challenges are divided into specific (allergenic) and non-specific. Typical clinical symptoms depend on the immunological reaction: sneezing, itching, rhinorrhea and nasal blockage. Eosinophilic mucosal infiltration is observed in the late phase reaction. Typically the result of nasal challenge should be assessed by the physician and patient. The immunological reaction, especially the level of particular allergenic mediators, could also be investigated. Some objective methods for final assessment of the results are recommended. There is some information about non-specific nasal provocation with aspirin and occupational diseases in the paper.

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Standards of nasal provocation tests

nasal provocation test, diagnosis of allergy, aspirin test