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eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
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without publication fees
6/2017
vol. 104
 
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abstract:
Special paper

Systemic sclerosis – diagnostic and therapeutic recommendations of the Polish Dermatological Society. Part 2: treatment

Dorota Krasowska
,
Lidia Rudnicka
,
Aleksandra Dańczak-Pazdrowska
,
Grażyna Chodorowska
,
Anna Woźniacka
,
Anna Lis-Święty
,
Joanna Czuwara
,
Joanna Maj
,
Sławomir Majewski
,
Anna Sysa-Jędrzejowska
,
Anna Wojas-Pelc

Dermatol Rev/Przegl Dermatol 2017, 104, 583-596
DOI: https://doi.org/10.5114/dr.2017.71831
Online publish date: 2017/12/05
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Systemic sclerosis is an immune-mediated disease characterized by a chronic progressive course. The complex and diverse clinical features seen in patients require case-by-case approach and cooperation of multiple specialists both at the stage of diagnosis and treatment. Critical factors in systemic sclerosis include early diagnosis, assessment of internal organ involvement, identification of patients at potential risk of organ complications, assessment of disease dynamics and activity, and implementation of optimal therapy. Treatment decisions should be made individually for each patient after careful consideration of such aspects as the severity of skin lesions, duration and activity of the disease, manifestations and possible internal organ involvement. On account of potential organ dysfunctions, patients require a multidisciplinary therapeutic approach and coordinated treatment by experienced specialists or in specialist medical centres. Part 2 presents current guidelines for the treatment of systemic sclerosis.
keywords:

methotrexate, alprostadil, sildenafil, mycophenolate mofetil, cyclophosphamide, scleroderma, guidelines
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