The incidence rate of hospitalized lysosomal storage diseases in Poland 
in 2013-2015 based on data from the National Health Fund

Władysław Grzeszczak; Edward Franek; Agnieszka Szypowska; Winicjusz Filipow; Mariusz Zięba; Paweł Kabicz; Barbara Więckowska

doi:10.5114/pedm.2021.107715

Abstract

3/2021 vol. 27

Original paper

The incidence rate of hospitalized lysosomal storage diseases in Poland in 2013-2015 based on data from the National Health Fund

Władysław Grzeszczak ¹

,

Edward Franek ^{2, 3}

,

Agnieszka Szypowska ⁴

,

Winicjusz Filipow ⁵

,

Mariusz Zięba ⁶

,

Paweł Kabicz ⁶

,

Barbara Więckowska ^{6, 7}

Chair and Department of Internal Medicine, Diabetology, and Nephrology, Silesian University of Medicine, Zabrze, Poland
The Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
Department of Internal Diseases, Endocrinology and Nephrology, Central Clinical Hospital of the Ministry of Interior Affairs and Administration, Warsaw, Poland
Department of Paediatrics, Medical University of Warsaw, Warsaw, Poland
Department of Research and Development and Innovative Medicine for Metabolic Diseases at the Diabetic Clinic, Nysa, Poland
Department of Analyses and Strategy, Ministry of Health, Warsaw, Poland
Social Insurance Department of the Warsaw School of Economics, Warsaw, Poland

Pediatr Endocrinol Diabetes Metab 2021; 27 (3): 191–198

DOI: https://doi.org/10.5114/pedm.2021.107715

Online publish date: 2021/08/28

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AMA

Grzeszczak W, Franek E, Szypowska A, et al. The incidence rate of hospitalized lysosomal storage diseases in Poland in 2013-2015 based on data from the National Health Fund. Pediatric Endocrinology Diabetes and Metabolism. 2021;27(3):191-198. doi:10.5114/pedm.2021.107715.

APA

Grzeszczak, W., Franek, E., Szypowska, A., Filipow, W., Zięba, M., & Kabicz, P. et al. (2021). The incidence rate of hospitalized lysosomal storage diseases in Poland in 2013-2015 based on data from the National Health Fund. Pediatric Endocrinology Diabetes and Metabolism, 27(3), 191-198. https://doi.org/10.5114/pedm.2021.107715

Chicago

Grzeszczak, Władysław, Edward Franek, Agnieszka Szypowska, Winicjusz Filipow, Mariusz Zięba, Paweł Kabicz, and Barbara Więckowska. 2021. "The incidence rate of hospitalized lysosomal storage diseases in Poland in 2013-2015 based on data from the National Health Fund". Pediatric Endocrinology Diabetes and Metabolism 27 (3): 191-198. doi:10.5114/pedm.2021.107715.

Harvard

Grzeszczak, W., Franek, E., Szypowska, A., Filipow, W., Zięba, M., Kabicz, P., and Więckowska, B. (2021). The incidence rate of hospitalized lysosomal storage diseases in Poland in 2013-2015 based on data from the National Health Fund. Pediatric Endocrinology Diabetes and Metabolism, 27(3), pp.191-198. https://doi.org/10.5114/pedm.2021.107715

MLA

Grzeszczak, Władysław et al. "The incidence rate of hospitalized lysosomal storage diseases in Poland in 2013-2015 based on data from the National Health Fund." Pediatric Endocrinology Diabetes and Metabolism, vol. 27, no. 3, 2021, pp. 191-198. doi:10.5114/pedm.2021.107715.

Vancouver

Grzeszczak W, Franek E, Szypowska A, Filipow W, Zięba M, Kabicz P et al. The incidence rate of hospitalized lysosomal storage diseases in Poland in 2013-2015 based on data from the National Health Fund. Pediatric Endocrinology Diabetes and Metabolism. 2021;27(3):191-198. doi:10.5114/pedm.2021.107715.

Introduction

The reported data address the incidence of lysosomal storage diseases, obtained from the public health service databases in Poland. Data are given by subtypes from the National Health Fund between 2013 and 2015.

Material and methods

Patients with lysosomal storage diseases were identified in the National Health Fund database (2013–2015). In order to ensure that the reported incidence data included only new patients. The geographic area of residence in 2013–2015 was divided into 6 parts.

Results

The incidence rate of lysosomal storage diseases in Poland is about 1.84/1 million/person/years. Other sphingolipidosis was the largest disease category, with 127 patients (incidence 1.1 patients/million habitants), follow by GM2 gangliosidosis – 29 patients (incidence 0.25 patients/million habitants). Men had a somewhat higher incidence than women (respectively IR = 2.53, IR = 1.84). The number of deaths with lysosomal storage disease patients hospitalized between the years 2013 through 2015 is higher in young people (0–9 years old).

Conclusions

The incidence rate of lysosomal storage diseases in Poland is about 1.84 per million person-years. Other sphingolipidosis was the largest disease category, followed by GM2 gangliosidosis. The hospitalization rate of lysosomal storage diseases was higher in men.

Keywords

lysosomal storage diseases, incidence rate, 2013–2015, Poland