The use of photodynamic therapy in combined treatment of actinic keratosis

Katarzyna Małkińska; Joanna Bartosińska; Mirosław Kwaśny; Dorota Krasowska

doi:10.5114/dr.2020.103889

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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6/2020
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abstract:

Review paper

The use of photodynamic therapy in combined treatment of actinic keratosis

Katarzyna Małkińska

¹

,

Joanna Bartosińska

²

,

Mirosław Kwaśny

³

,

Dorota Krasowska

⁴

Klinika Dermatologii, Wenerologii i Dermatologii Dziecięcej, Samodzielny Publiczny Szpital Kliniczny nr 1 w Lublinie, Polska

Zakład Kosmetologii i Medycyny Estetycznej, Uniwersytet Medyczny w Lublinie, Polska

Instytut Optoelektroniki Wojskowej Akademii Technicznej im. Jarosława Dąbrowskiego w Warszawie, Polska

Katedra i Klinika Dermatologii, Wenerologii i Dermatologii Dziecięcej, Uniwersytet Medyczny w Lublinie, Polska

Dermatol Rev/Przegl Dermatol 2020, 107, 534-545

DOI: https://doi.org/10.5114/dr.2020.103889

Online publish date: 2021/02/27

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Actinic keratosis, a type of squamous cell carcinoma in situ, is characterised by hyperkeratotic focal lesions formed on the ultraviolet-damaged skin. Usually, there are a few to several so foci of actinic keratosis, and less often a single lesion is present. The treatment depends on the number, size, duration, and location of lesions. This study discusses some options of combined treatment of actinic keratosis and the possible risk of cancer associated with the use of photodynamic therapy in combination with laser therapy, topical medications (imiquimod, 5-fluorouracil, diclofenac, topical retinoids, ingenol mebutate, calcipotriol), and microneedling. Combined treatment is worth considering in cases of numerous hyperkeratotic foci, particularly in difficult-to-treat locations. Effective photoprotection is essential for all persons with actinic keratosis.

keywords:

The use of photodynamic therapy in combined treatment of actinic keratosis

Katarzyna Małkińska 1 , Joanna Bartosińska 2 , Mirosław Kwaśny 3 , Dorota Krasowska 4

actinic keratosis, photodynamic therapy, combined treatment

Katarzyna Małkińska

¹

,

Joanna Bartosińska

²

,

Mirosław Kwaśny

³

,

Dorota Krasowska

⁴