Przegląd Dermatologiczny

Abstract

2/2021 vol. 108
Case report

Simultaneous endemic pemphigus foliaceus and psoriasis vulgaris in Peru – immunogenetic or environmental factors?

  1. Instituto de Investigaciones Clínicas, Universidad Nacional Mayor de San Marcos, Lima, Peru
  2. Universidad Católica Santo Toribio de Mogrovejo, Chiclayo, Peru
  3. Instituto Nacional de Salud, Lima, Peru
  4. Universidad de San Martin de Porres, Lima, Peru
  5. Department of Dermatology, Oregon Health & Science University, Portland, OR, USA
Dermatol Rev/Przegl Dermatol 2021, 107, 153-159
Online publish date: 2021/06/28
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Endemic pemphigus foliaceus is a rare autoimmune disease typically reported in isolated geographical areas. It is characterized by subcorneal blisters and presence of IgG4 anti-desmoglein 1 autoantibodies. Although a meta-analysis and several case reports suggest an association between pemphigus foliaceus and psoriasis vulgaris, there have been no case reports of endemic pemphigus foliaceus and psoriasis occurring simultaneously in the same patient. In this article, we present three cases depicting concurrent endemic pemphigus foliaceus and psoriasiform eruptions. In the first case, endemic pemphigus foliaceus preceded psoriasis vulgaris, in the second case psoriasis developed first and in the third case we could not determine the chronological order of these diseases. The literature related to this topic is discussed.
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