Abstract
5/2022
vol. 109
Review article
Conjunctivitis as a common adverse effect of dupilumab in atopic dermatitis
- Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland Katedra i Klinika Dermatologii, Wenerologii i Alergologii, Gdański Uniwersytet Medyczny, Gdańsk, Polska
Dermatol Rev/Przegl Dermatol Rev 2022, 109, 344–351
Online publish date: 2023/03/16
Dupilumab is a monoclonal antibody against the a subunit of the receptor for interleukin 4 and interleukin 13. It is the first biological drug registered in the world for the treatment of atopic dermatitis. Dupilumab turned out to be a milestone in the treatment of atopic dermatitis and an alternative to standard immunosuppressive drugs. In numerous multicenter studies, including real-life studies, it has been proven that dupilumab brings a significant improvement in subjective and objective clinical symptoms in atopic dermatitis. Conjunctivitis is one of the side effects of dupilumab treatment. It is estimated that it affects about 14% of patients with atopic dermatitis. The mechanisms leading to it are not yet fully understood.
Keywords
atopic dermatitis, dupilumab, conjunctivitis
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