eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
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SCImago Journal & Country Rank
2/2022
vol. 17
 
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Artykuł przeglądowy

Diet as therapeutic intervention in Crohn’s disease

Martyna Więcek
1
,
Paulina Panufnik
1
,
Karolina Pomorska
1
,
Konrad Lewandowski
1
,
Grażyna Rydzewska
1

  1. Clinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Subunit, Central Clinical Hospital of the Ministry of Interior and Administration, Warsaw, Poland
Gastroenterology Rev 2022; 17 (2): 96–102
Data publikacji online: 2022/05/19
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Diet plays an important role in the pathogenesis of inflammatory bowel disease. It has an impact on microbiome, host barrier, and immune response. Clinical studies indicate that various dietary interventions such as exclusive enteral nutrition and exclusion diets might be useful for induction of remission in mild to moderate Crohn’s disease, but also for patients failing biological therapy. Current treatment strategies try to solve the problem of poor patient compliance due to the required strict dietary regime. The number of adverse events associated with the use of dietary alternatives is incomparable with the side effects of glucocorticosteroids or biological treatment, which makes them a tempting therapeutic option.
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