An enormous pelvic tumor in a 46-year-old woman with an elevated 
serum CA 125 level, what lies beneath it? Investigation of uterine tumors 
in postmenopausal women

Francesk Mulita; Elias Liolis; Dimitrios Kehagias; Levan Tchabashvili; Charalampos Kaplanis; Fotios Iliopoulos; Ioannis Perdikaris; Ioannis Kehagias

doi:10.5114/pm.2021.109773

eISSN: 2299-0038
ISSN: 1643-8876

Menopause Review/Przegląd Menopauzalny

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3/2021
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abstract:

Case report

An enormous pelvic tumor in a 46-year-old woman with an elevated serum CA 125 level, what lies beneath it? Investigation of uterine tumors in postmenopausal women

Francesk Mulita

¹

,

Elias Liolis

¹

,

Dimitrios Kehagias

¹

,

Levan Tchabashvili

¹

,

Charalampos Kaplanis

¹

,

Fotios Iliopoulos

¹

,

Ioannis Perdikaris

¹

,

Ioannis Kehagias

¹

Department of Surgery, General University Hospital of Patras, Rio, Greece

Menopause Rev 2021; 20(3): 154-157

DOI: https://doi.org/10.5114/pm.2021.109773

Online publish date: 2021/10/11

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AMA

Mulita F, Liolis E, Kehagias D, et al. An enormous pelvic tumor in a 46-year-old woman with an elevated 
serum CA 125 level, what lies beneath it? Investigation of uterine tumors 
in postmenopausal women. Menopause Review/Przegląd Menopauzalny. 2021;20(3):154-157. doi:10.5114/pm.2021.109773.

APA

Mulita, F., Liolis, E., Kehagias, D., Tchabashvili, L., Kaplanis, C.,  & Iliopoulos, F. et al. (2021). An enormous pelvic tumor in a 46-year-old woman with an elevated 
serum CA 125 level, what lies beneath it? Investigation of uterine tumors 
in postmenopausal women. Menopause Review/Przegląd Menopauzalny, 20(3), 154-157. https://doi.org/10.5114/pm.2021.109773

Chicago

Mulita, Francesk, Elias Liolis, Dimitrios Kehagias, Levan Tchabashvili, Charalampos Kaplanis, Fotios Iliopoulos,  and Ioannis Perdikaris et al. 2021. "An enormous pelvic tumor in a 46-year-old woman with an elevated 
serum CA 125 level, what lies beneath it? Investigation of uterine tumors 
in postmenopausal women". Menopause Review/Przegląd Menopauzalny 20 (3): 154-157. doi:10.5114/pm.2021.109773.

Harvard

Mulita, F., Liolis, E., Kehagias, D., Tchabashvili, L., Kaplanis, C., Iliopoulos, F., Perdikaris, I.,  and Kehagias, I. (2021). An enormous pelvic tumor in a 46-year-old woman with an elevated 
serum CA 125 level, what lies beneath it? Investigation of uterine tumors 
in postmenopausal women. Menopause Review/Przegląd Menopauzalny, 20(3), pp.154-157. https://doi.org/10.5114/pm.2021.109773

MLA

Mulita, Francesk et al. "An enormous pelvic tumor in a 46-year-old woman with an elevated 
serum CA 125 level, what lies beneath it? Investigation of uterine tumors 
in postmenopausal women." Menopause Review/Przegląd Menopauzalny, vol. 20, no. 3, 2021, pp. 154-157. doi:10.5114/pm.2021.109773.

Vancouver

Mulita F, Liolis E, Kehagias D, Tchabashvili L, Kaplanis C, Iliopoulos F et al. An enormous pelvic tumor in a 46-year-old woman with an elevated 
serum CA 125 level, what lies beneath it? Investigation of uterine tumors 
in postmenopausal women. Menopause Review/Przegląd Menopauzalny. 2021;20(3):154-157. doi:10.5114/pm.2021.109773.

PlumX metrics:

Abdominal and pelvic pain with an associated pelvic mass is a very common emergency situation. There is always a management dilemma for most emergency physicians regarding these patients. A 46-year-old postmenopausal woman was admitted to our emergency department (ED) with complaints of massive abdominal distention. Abdominal and pelvis magnetic resonance imaging (MRI) was performed, which revealed a huge pelvic abdominal mass. All tumor markers were within normal limits. However, the ovarian cancer antigen (CA 125) level was elevated. As there was a strong suspicion of malignancy, the patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Her final histopathology report was suggestive of uterine leiomyoma. Uterine leiomyomas are the most common benign uterine tumors in women. Surgical treatment is the gold standard, especially for older women with severe symptoms and no desire for future fertility. Although the combination of a pelvic tumor and a high-level of CA 125 arouses suspicion of gynecological malignancy, other benign conditions should always be considered in the differential diagnosis. There is limited evidence to support an association between elevated CA 125 levels and uterine fibroids so far. However, conditions such as the coexistence of adenomyosis and tumor size can affect the level of this marker in uterine fibroids.

keywords:

An enormous pelvic tumor in a 46-year-old woman with an elevated serum CA 125 level, what lies beneath it? Investigation of uterine tumors in postmenopausal women

Francesk Mulita 1 , Elias Liolis 1 , Dimitrios Kehagias 1 , Levan Tchabashvili 1 , Charalampos Kaplanis 1 , Fotios Iliopoulos 1 , Ioannis Perdikaris 1 , Ioannis Kehagias 1

menopause, uterine tumor, CA 125, leiomyoma

Francesk Mulita

¹

,

Elias Liolis

¹

,

Dimitrios Kehagias

¹

,

Levan Tchabashvili

¹

,

Charalampos Kaplanis

¹

,

Fotios Iliopoulos

¹

,

Ioannis Perdikaris

¹

,

Ioannis Kehagias

¹